Even if space is limited in your home, your should have some area that is designated as a home office.  If you take the time to organize it well, you will easily be able to deal with paperwork, bills, lists, planning, etc..

When the space allows for it, use an L-shaped desk, so that you can still have full use of one surface when there is a computer, monitor, and printer that are always up and in use.  A slide or hinged area for your keyboard will allow you to push it out of the way when not using it.

If you are going to be spending a lot of time at the desk, try to invest in a good chair.  Have a small adjustable footstool under the desk so that you can ease your back by changing positions and angles now and then.

A two-drawer file cabinet placed next to the desk will be very handy for storing paid bills, etc. Place in/out files on top, and perhaps a desk lamp.  In fact, task lighting should be available in all three work areas…at the computer, on the main part of your des, and over the file cabinet.  Overhead lights cause glare on monitor screens.

If you have the room for it, you should have a table height credenza running parallel to your desk.  This allows you to spread out, and also to have paper, clips, stapler, and so on available by simply swiveling your chair.  However, if you don’t, pick up on of those long folding tables they use for picnics, and open it up when you are working on a large project.